Does insulin create difficulty in losing weight? and does 8 yearsof using it upset my hormones?

Yes and No: One of the side effect of Insulin is weight gain. That's why it's important to follow your doctor's advise and use only what's necessary to control your blood sugar. There are other diabetes medication you can use along with Insulin to negate the weight gain from insulin. Using Insulin long term does not "upset your hormones." chances are if you are on it, then your doc thinks you need it.