A member asked:

I have pcos and metformin is really tearing my stomach lining. i have ibs as well. what medicinecould zi suggest to my doctor other than metformin?

8 doctors weighed in across 3 answers

Metformin: It depends in part on what symptom you are treating. With metformin make sure you are on er- extended release as it causes less stomach problems often. Also make sure you go up on the dose very slowly. Start with the lowest possible dose and only go up on the dose after a few weeks. Many people who don't tolerate meformin going to a high dose quickly, can tolerate it they take it very slowly.

Answered 10/12/2012

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MetforminXR: We have seen very limited results with extended release metformin. The trick is to start at a low dose. Take it with a full stomach. If you skip a meal skip the dose. Most important be sure to follow a low glycemic, low processed carbs diet.

Answered 6/10/2015

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Actos (pioglitazone) or Byetta: These two drugs have been used for pcos but not commonly. Actos (pioglitazone) however can cause weight gain, and Byetta is expensive and probably would not be covered by insurance for pcos. Make sure you are not taking the metformin on an empty stomach.

Answered 6/24/2014

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