A 41-year-old female asked:
a patient with copd was receiving 12.5mcg of fentanyl. the gp double this dose to 25mcg. the patient died two weeks later. is there any correlation?
2 doctor answers
Dr. Dan Fisher answered
26 years experience Internal Medicine
Not likely.: From the info given it is too hard to tell, but doesn't seem likely. The additional respiratory and nervous system depression related to the dose increase would be very minor. There are many possible reasons to die suddenly and unexpectedly..... Some of these could be related to the COPD and some could be related to the reason the person was taking fentanyl to begin with.
Answered on Jul 12, 2018
Dr. Jaymin Chang answered
20 years experience Anesthesiology
Impossible to tell: ...Based on the information provided. We don't know the pt's other comorbidities, concurrent drugs, what the pt's disposition was at the time of death (was he driving? Intubated in the icu? Drinking? Exercising? Sleeping?) it would be speculation at best, but it seems unlikely that the increase in fentanyl dosage directly caused death because the pt tolerated it for two weeks prior t.
Answered on Nov 22, 2017
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