Can you feel supraclavicle lymph nodes?

Yes if enlarged: Normally you cannot feel them because they are very small and soft. If they are enlarged due to infections, cancer etc. They may be felt.

Monitoring Centers: Lymphatic system absorbs/carries things too big to go into the arteries/veins like bacteria eaten by white cells and digested food. Lymph nodes "taste" the lymph for anything bad like bacteria, viruses, cancers, etc. When it detects a problem, it alerts the immune system and your body reacts. They enlarge in response to the inflammation they create when they react. They shrink when all is well.