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A member asked:
Why is tylenol (acetaminophen) so damaging to the liver?
A doctor has provided 1 answer
Over-dose - NAPQI: Tylenol (acetaminophen) is metabolized by the liver with a by product called n-acetyl-p-benzoquinoneimine (napqi). Napqi damages hepatocytes (liver cells). If you take an over-dose of tylenol (acetaminophen) there is too much napqi to safely remove through urine. The napqi damages the liver.
Answered 9/29/2013
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