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A member asked:

Why is tylenol (acetaminophen) so damaging to the liver?

A doctor has provided 1 answer
Dr. Heidi Fowler answered

Specializes in Psychiatry

Over-dose - NAPQI: Tylenol (acetaminophen) is metabolized by the liver with a by product called n-acetyl-p-benzoquinoneimine (napqi). Napqi damages hepatocytes (liver cells). If you take an over-dose of tylenol (acetaminophen) there is too much napqi to safely remove through urine. The napqi damages the liver.

Dr Ali and another doctor agreed

Answered 9/29/2013

5.3k views

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Tuesday and Wednesday I took 30 childrens tylenol (acetaminophen) (80mg) since Thursday I've takin 80 tablets of extra strength Tylenol (acetaminophen) (500mg). Well I develop liver damage?

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