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A member asked:
Is topical spironolactone (2%) safe for mpb? is it effective? can systemic absorption occur?(coz its 50-75 mg topical application in paraben vehicle)
A doctor has provided 1 answer
Topical Spironolacto: The literature on systemic absorption of topical sprironolactone is a bit unclear. Small studies in lab rodents showed no absorption, but there are numerous anecdotal entries on hair loss blogs where users attest to side effects which point towards systemic absorption, including falling testosterone levels. Monitor your use carefully to see if you are an "absorber.".
Answered 3/5/2013
5.3k views
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