Bumps (itchy and painful) appear on my scalp for the past 2yrs that lead to hairloss when irritated. prescribed minocycline but still have symptoms?

Various: There are many causes of bumps on the scalp, including infection, acne, and bumps that come from significant scratching of the scalp. If Minocycline isn't working, seek a health professional for continued evaluation.

Topical Clindamycin: You likely have folliculitis, an inflammation of the hair follicles. Minocin (minocycline) is often helpful but can take several months to be fully effective. You can ask your doctor for a prescription of topical Clindamycin solution. You can also try a tar shampoo like t-gel by neutrogena.