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A 40-year-old male asked:

8.5 yrs daughter with bone age of 11.5 yrs. mri: diffused enlargement of pituitary gland 10.5x7.3x7.8mm with no focal lesion. how abnormal is the size

1 doctor answer1 doctor weighed in
Dr. Shari Jackson
Radiology 21 years experience
A bit tricky: The pituitary grows during childhood and peaks in the 2nd or 3rd decade. Most studies measuring pituitary size on MRI focused only on the height of the pituitary gland and find that the mean peak height is usually about 6 mm +/- 1 mm. More recent studies measure the actual volume of the pituitary with special 3d mri. The mean volume for 5-9 yo girl in one study was 336+/-113 mm3.

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Last updated Jun 10, 2014
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