A member asked:

Are there any known causes of persistent corpus luteum?

4 doctors weighed in across 2 answers

Yes: Fertility drug treatments (like Clomid (clomiphene) and injectable meds like HCG and hmg and fsh) increase the odds of forming corpus luteum cysts that can persist beyond the typical luteal phase duration. On "natural" cycles (no meds), it can happen for unknown reasons but is less common.

Answered 6/24/2014

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Pregnancy: Most common cause of persistent corpus luteum is pregnancy. If not pregnant, one cause of persistent cysts is use of ovulation induction agents such as Clomiphene citrate or gonadotropins. The more follicles/corpus luteum that is formed, the more that is needed to be reabsorbed by the ovary by the time of the next menses if not pregnant.

Answered 6/24/2014

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