Us it safe to use tramadol 400mg as needed, with doxepin 150mg @ bedtime? recently diagnoses with sinus tachycardia? doctor recently prescribed both.

Some caution: Combination may increase CNS depression, psychomotor impairment, cause low blood pressure, and rarly cases a syndrome of intense serotonin release that can be dangerous. Probably safe short tern in loe to moderate doses.

Tachycardia: Doxepin should be avoided with tachycardia since it has anticholinergic properties and will worsen the tachycardia.