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A member asked:

Any problems from taking 5 mg amlodipine @ 7 pm, and 10 mg simvastain @ 10 pm. how far can you space them a part to be safe from interactions. ?

2 doctors weighed in across 3 answers

Interact: The amlodipine can interact (delay) how Simvastatin is metabolized leading to higher blood levels and potentially side effects. This usually happens at higher doses of Simvastatin . My practice is to avoid using the two in combination. Speak with your doctor.

Dr Koch agreed

Answered 6/24/2014

5.3k views

Thank
Dr. Rick Koch answered

The issue: Is not the timing. Maximum dose of Simvastatin is 20mg while on amlodipine. 10mg should not be a problem.

Answered 8/12/2018

5.3k views

Thank
Dr. Rick Koch answered

The issue: Is not the timing. Maximum dose of Simvastatin is 20mg while on amlodipine. 10mg should not be a problem.

Answered 6/24/2014

5.3k views

Thank

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