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A member asked:
Can acid reflux cause esophageal cancer without ever having barretts esophagus?
4 doctors weighed in across 2 answers
Let me explain: A particular enzyme is significantly higher in cancer cells that have been exposed to acid, leading to the overproduction of hydrogen peroxide, and offering a possible explanation for how acid reflux may lead to cancer of the esophagus, according to a recent study in the journal of biological chemistry.
Answered 3/25/2019
5.3k views
Yes and no: Acid reflux is not clearly a cause of esophageal cancer. But there is an association of reflux (acid and non-acid) to barrett's esophagus/adenocarcinoma of the esophagus. There are other types of esophageal cancers, which may or may not be related to reflux.
Answered 12/24/2014
5.3k views
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