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A member asked:
How does dengue fever leads to hepatomegaly?
4 doctors weighed in across 2 answers
Liver Infection: The dengue virus infects the liver cells. Google pathogenesis of liver involvement during dengue viral infections.
Answered 12/6/2017
5.4k views
Multiple factors: Clinical evidence of liver involvement in dengue infections includes the presence of hepatomegaly and increased serum liver enzymes. Dengue viral antigens have been found within hepatocytes, and the virus appears to be able to replicate in both hepatocytes and kupffer cells, and dysregulated host immune responses may play an important causative role in liver damage.
Answered 7/9/2018
5k views
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