Hepatomegaly: Hepatic dysfunction is a well recognized feature of dengue infections, often demonstrated by hepatomegaly and mild-to-moderate increases in transaminase levels although jaundice and acute liver failure are generally uncommon. Debate continues as to whether dengue associated hepatic dysfunction indicates a direct viral effect, arises secondary to an aggressive host immune response to the virus, or reflects a complex interaction of these two mechanisms.
Answered 4/19/2015
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