Not many: Zoloft (sertraline) and trazodone are often prescribed together. Some people find that zoloft (sertraline) can interfere with sleep and trazodone often provides the necessary sleep relief. Make sure to take trazodone at bedtime, and i would recommend taking zoloft (sertraline) in the morning. Zoloft (sertraline) and trazodone each have side effects, but their combination does not tend to cause other effects separate from those side effects.
Answered 8/2/2020
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