Usually yes: While both Zoloft (sertraline) and naproxen can cause bleeding, Zoloft (sertraline) by increasing serotonin in platelets, which are essential for blood to clot, and naproxen by causing irritation of stomach lining and thereby increasing the risk of bleeding ulcers, most patients taking Zoloft (sertraline) and other serotonin antidepressants (SSRIs) can take naproxen without adverse effects.
Answered 7/6/2018
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