Get Virtual Care
For Businesses
About Us
A member asked:
When i take a benadryl (diphenhydramine) at night before i go to bed why do i always wake up with a horrific headache that lasts for about 45 min?
A doctor has provided 1 answer
Known side effect: Benadryl (diphenhydramine) can cause headache in certain patients (mechanism unknown). If you are taking Benadryl (diphenhydramine) at night to help you get to sleep, I have had many patients do well taking melatonin (3 mg - over the counter) instead.
Answered 3/9/2018
5.4k views
Thank
Related Questions
A member asked:
I am 11 and a half week pregnant and having bad sinus pressure and headaches. Is Benadryl (diphenhydramine) safe to take at 11 weeks?
4 doctors weighed in across 2 answers
A member asked:
Can i take Benadryl (diphenhydramine) severe allergy plus sinus headache with advil?
2 doctors weighed in across 2 answers
A member asked:
My husband doctor has him taking a Z pack and Amox-Clav 875mg and Benadryl (diphenhydramine). He has a huge headache and wants to take an 800 mg ibuprofen. Can he ?
A doctor has provided 1 answer
A member asked:
I have a sinus headache due to a cold. I took a 24 hour claritin pill this morning, but it didnt help. Can i take benadryl (diphenhydramine) now? Its only been 12 hrs.
A doctor has provided 1 answer
A member asked:
Been dealing with headaches for weeks day and nit and taken Advil left and right I want to stop. I take Maxalt too. Could I try Benadryl (diphenhydramine) or melatonin.
A doctor has provided 1 answer
People also searched for:
I've been taking Benadryl (diphenhydramine) at night and now I can't sleep if I don't take it. I have huge headaches what can I do?
I'm 16 & took 4 tablets of Benadryl (diphenhydramine) I usually take 3 a night to help me sleep but I took 4 & now I got a headache can I take something for that?
Bug bite to face last night. Today, top lip swollen, aching teeth and headache. Took OTC Benadryl (diphenhydramine) with some help, but symptoms return.
I just started zoloft today along with Buspirone and have a headache, can I take a benadryl (diphenhydramine)?
I took 2 Excedrin tension pills.. Can I take 2 Benadryl (diphenhydramine) sinus headache on top of that?
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HIPAASecure
SOC 2 Type 2Certified
JCAHOAccredited
Download HealthTap
Video visit and message your doctor
