What other treatment that folfox for 6 months do you reccomend for someone with a stage 3b colon cancer t4 , n1c without lymph nodes involvement? any o

Tough one: Well if it is n1, than lymph nodes are positive. If n0 that means lymph nodes are clear or negative. I think folfox 6 months is usually given for stage 3 (lymph node +) disease. Ilook at age, family history, grade of tumor, lvi, oncotype recurrence score if MMR +, perforation or not and if pt really high risk, than 2 years of Xeloda (capecitabine) as risk of relapse is high in first 2 yrs. It is not standard.

Other similar ones: Folfox is probably the better tolerated one. By the way, if this is stage iii colon cancer, lymph nodes must be present (as in n1) in the staging evaluation. There are other so called adjuvant treatments (given after surgery) but they are all variations of folfox. There are older treatments too (5fu (fluorouracil) (fluorouracil) and levamisole, 5fu (fluorouracil) and leucovorin), but they are inferior. We don't use folfiri postop in the us.

FOLFIRI is similar,,: First, if you are n1, then one lymph node is positive, so you are likely at a stage with regional lymph node involvement, or dukes stage c. Standard therapy is with 5 fuorouracil (5-fu ) and levamisole with CEA level follow up. Folfox is 5-fu, oxaliplatin (eloxatin) and folinic acid (leucovorin), while folfiri is irinotecan (camptosar), with 5-fu and leucovorin and are given in 2 wk cycles.