Big dose less effect: Many physicians prefer a daily dose of 5, 000-8, 000 iu of vitamin d3. A once weekly dose of 50, 000 iu is safe, but not as helpful due to poor absorption of a single dose of 50, 000 iu. Once 25 hydroxy vitamin d levels reach 60 - 80, the daily dose (5, 000-8, 000 iu) is usually cut in half and the patient followed to ensure the new dose is able to maintain therapeutic vitamin d levels.
Answered 12/6/2019
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