A member asked:

Should t3 (liothyronine) and t4 levels be equal or is there a ratio between the two?

2 doctors weighed in across 2 answers
Dr. David Geffner answered

Specializes in Endocrinology

None: The thyroid produces mostly t4, very little t3 (liothyronine). T3 (liothyronine) is created in the nuclei of all your cells from T4 which it takes in. The ratio of T4 to T3 (liothyronine) actually circulating in the blood is quite high.

Answered 1/15/2015

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Dr. Su Fairchild answered

Specializes in Integrative Medicine

Not quite: T4 is a storage (inactive) form of thyroid hormone that is converted to T3 (liothyronine) (active form) and reverse t3 (liothyronine). Think of T3 (liothyronine) as the gas and rt3 (liothyronine) as the brakes. The more important ratio is that of T3 (liothyronine) to reverse t3 (liothyronine). You want more gas than brakes.

Answered 1/15/2015

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