What symptoms are different in schizophrenia and schizoaffective disorder? is one a disease of the brain, other disorder?

Both brain disease: Both of these illnesses are "brain diseases, " and both have psychotic symptoms such as delusions, paranoia, hallucinations, thought disorder, etc. Schizoaffective patients also have mood dysregulation, but pure schizophrenics don't. Treatment for schizophrenia may be antipsychotics alone; schizoaffective people also need mood stabilizing agents. They may deal with mania & depression, + psychosis.