A member asked:

It's been six years since my dad has had prostate cancer. he has had radiation and hormone therapy. now his gleason numbers are high now spots on spin. what doesit mean?

5 doctors weighed in across 3 answers
Dr. Mathew Sorensen answered

Specializes in Urology

Cancer: It is not entirely clear, but it sounds like he may have recurrent cancer after his treatment? Keep your spirits up, while a cure may be unlikely, there are now lots of treatment options which can slow down the cancer so that it is less lifethreatening.

Answered 9/25/2016

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Dr. Terence Chapman answered

Specializes in Urologic Oncology

May have returned: Unfortunately this may mean that your father's cancer has progressed despite treatment. A high gleason score (8-10) independently predicts the odds of this as well as high psa score and abnormal exam findings. Fortunately there are many highly effective treatments available even in situations where the cancer has spread. An oncologist can help you decide on appropriate treatments for your father.

Answered 12/10/2015

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PSA: Gleason is used to describe how aggressive the cancer is not how a pt is doing. Your dad's psa is the key...If it is going up on hormone treatment he has hormone refractory prostate ca, he may need more aggressive testosterone blockage.

Answered 1/4/2014

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