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A member asked:
With regards to hla typing, is mhc-1 matching or mhc-2 better to avoid a graft rejection?
A doctor has provided 1 answer
In the arena of stem: Cell transplantation this is more defined than in the past. Class one match (hla a, b and c) and class two (hla dr and dq) are all performed at high resolution (gene level tryping). The best match with all loci evaluated will produce the lowest chance of graft rejection. Mis-match can be assessed in the gvhd and host vs graft (rejection) direction.
Answered 12/24/2012
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