What is the pathology of colorectal cancer ?

Adenocarcinoma: Colorectal cancer is usually adenocarcinoma that developed from a underlying polyp. For details on staging visit http://www.Cap.Org/apps/cap.Portal?_nfpb=true&cntvwrptlt_actionoverride=%2fportlets%2fcontentviewer%2fshow&_windowlabel=cntvwrptlt&cntvwrptlt%7bactionform.Contentreference%7d=committees%2fcancer%2fcancer_protocols%2fprotocols_index.Html&_state=maximized&_pagelabel=cntvwr.

Epithelial changes: The epithelium is the lining of the colon and rectum. These cells function to lubricate the stool as it passes through, and to reabsorb water out of the stool into the blood stream. Over a lifetime, there is a tremendous amount of regeneration of this tissue, just like your skin. Over time, mutations occur and the epithelium grows in an unregulated fashion, resulting in colorectal cancer.