Pathology report: mixed protoplasmic astocytoma and olichdendroglioma grade 2. does that mean cancer?

Yes: This is a description of a type of brain cancer. You need to talk with a/your neurosurgeon about this in greater detail for the appropriate management.

Yes: Protoplasmic astrocytoma and oligodendroglioma are both malignancies (cancers) arising from the brain tissue. Astrocytomas arise from the astrocytes in the brain and oligodendrogliomas arise from oligodendrocytes. A mixed tumor shows features of both.