A member asked:

What is the definition or description of: brca1 gene?

6 doctors weighed in across 3 answers

See below: This is a genetic mutation that puts a person at increased risk for breast and ovarian cancer. It is passed from parent to child with a 50% likelihood. Over a lifetme, people with a brca1 mutation have about a 60% chance of developing breast cancer and a slightly lower risk of developing ovarian cancer.

Answered 12/28/2012

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Prevent cancer: The brca1 gene is a tumor suppressor gene, a gene involved in decreasing the likeliness of developing cancer. A mutation in this gene can increase the likelihood of certain cancers including breast and ovarian cancers. For more information see: http://www.Cancer.Gov/cancertopics/factsheet/risk/brca.

Answered 2/23/2014

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Dr. Travis Kidner answered

Specializes in Surgical Oncology

Hereditary Cancer: Mutations in the brca genes lead to a increased risk for breast and ovarian cancer. Patients with mutations in brca have an 80% chance of developing breast cancer and a 40% change of developing ovarian cancer. It is recommended that these patients undergo bilateral mastectomies and also have their ovaries removed once their families are complete.

Answered 10/30/2013

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Related Questions

A member asked:

Whats cause and effect of brca1 gene on breast cancer?

13 doctors weighed in across 2 answers