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Dr. James Gulley

Hematology and Oncology
Bethesda, MD
28 years experience male

Locations

NIH Clinical Center

Bethesda, MD

Address

10 Center Dr. , Bethesda, MD
Directions

About

Bio

I am a senior investigator at the National Institutes of Health. I head a clinical trials group devoted to immunotherapy for cancer with a emphasis on prostate cancer.

Specialties
Doctors may have more than one area of specialty interest. Board certification in a specialty area means the doctor has completed formal training and has practice experience in that specialty, and has passed the certification examination from the corresponding accredited medical specialty board.

Hematology and Oncology

Languages spoken

English

Doctor Q&A

80 Answers
70 Agrees
The number of answers this doctor has agreed with.
A 41-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Increased: It depends on the type of exposure and amount of asbestos you were exposed to. Certainly asbestos is linked with mesothelioma and the risk increases i... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 43-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Explore options: The best source for information on clinical trials for patients with cancer is http://www.Cancer.Gov/clinicaltrials. This site has clinical trials fro... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 32-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Needs evaluation!: This is a difficult question with no easy answers. However ldh elevation indicates that there are cells that are being killed. The protein in the urin... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 81-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
A standard option: Provenge (sipuleucel-t) is a standard option for men who have progressive disease despite hormonal therapy and no or minimal symptoms. It probably is ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Targeted therapy: Newer targeted therapy agents can be quite beneficial for some patients with lung cancer. This is especially true in female never smokers who may hav... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 47-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Good: Most patients are able to recover platelet counts and have a mortality rate similar to the general population. For more details see this link. http:/... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 43-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
It depends: There are a variety of different subtypes of aml. See this link for further details. http://www.cancer.gov/cancertopics/pdq/treatment/adultaml/patient... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 41-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Synovial sarcoma: Synovial sarcoma usually occurs in the joints of the legs or arms and often occurs in younger individuals. Generally this presents as a painless swell... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 21-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Anemia: Fatigue can because by many medical conditions including anemia. Low blood counts can be due to many things. Taking iron supplementation may not help ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 41-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Possibly.: This may be done on a case-by-case basis depending on what the underlying bleeding disorder is and how easily this is corrected. Consult the transplan... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 38-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Not convinced: From the numbers above i'm not convinced that you have iron deficiency anemia. What was your mcv? There certainly could be other scenarios that would ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 41-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
See doctor: It could be late graft versus host disease in the colon.
Created for people with ongoing healthcare needs but benefits everyone.
A 36-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Yes: Radiation oncologists deliver external beam radiation therapy. The radiation is only present when the beam is turned on and is only present where the ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 31-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Prostate removal: The most common reason to remove the prostate is for localized prostate cancer. The procedure is called radical prostatectomy. However if a male patie... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 41-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Small bowel obstruct: Small bowel obstruction is seen frequently in patients following initial treatment for ovarian cancer. Any surgery or cancer in the peritoneum can giv... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 46-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Asymptomatic LN: I assume you mean swollen lymph nodes without any symptoms. This can be from a variety of different things. Infection generally causes symptoms howeve... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 30-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
It depends: The swollen lymph nodes and elevated white count could be because of an infection or an abnormality in the white blood cells.
Created for people with ongoing healthcare needs but benefits everyone.
A 32-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
No easy answer: I would discuss with your referring doctor. Some reference laboratories are much better than others. You can always have it sent to a third laboratory... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 24-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Prostate screening: There is significant controversy surrounding when and if to undergo screening for prostate cancer. For patients who have no symptoms most guidelines w... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Get checked out: You should get this area checked out. It could be nothing but it could be a cancer as you questioned. Only a detailed examination by a trained practit... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Always hope: There are many different levels of aggressiveness with prostate cancer however most are not progressive. It is possible that even without treatment th... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 31-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Many possibilities: This hard lump could represent infection cancer or potentially something else. This should be evaluated by a physician.
Created for people with ongoing healthcare needs but benefits everyone.
A member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Immune booster: Provenge (sipuleucel-t) is designed to train your body's immune system to recognize an attack your cancer cells. In a large controlled trial, Provenge... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 43-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Normal diet: Unless there is expected to be prolonged neutropenia, the diet can be anything you feel like eating. Many times chemotherapy well decrease the appetit... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 48-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Clinical research: All clinical trials require extensive review for scientific rationale and safety before starting. Clinical trials are conducted by specialists who see... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 22-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Usually not: The prostate exam is generally done with a lubricated gloved finger. If the examiner is gentle and allows the muscles of the anus to relax this usuall... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 21-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Not sure: This could be an autoimmune disease (like lupus) where the body's immune system is attacking the kidneys. It is less likely to be cancer related.
Created for people with ongoing healthcare needs but benefits everyone.
A member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
ALL: Acute lymphoblastic leukemia is treatable on relapse however without treatment often is rapidly fatal. There are many excellent centers that treat all... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 28-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Removal of plasma: It is a procedure whereby blood is taken out of the patient the blood cells are separated from the liquid or plasma and then the blood cells are given... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 69-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Off label: Neither zoledronate nor Denosumab is approved for disease that has not progressed on initial hormonal therapy. I would recommend waiting until diseas... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 42-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Not likely: Lymph nodes involved with cancer are typically hard, immovable and do not go away after a couple of minutes.
Created for people with ongoing healthcare needs but benefits everyone.
A 43-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
B symptoms: Symptoms can include fever, night-sweats and weight loss for both non-hodgkin's lymphoma and hodgkin's disease. These are referred to as b symptoms an... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 28-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Prevent cancer: The brca1 gene is a tumor suppressor gene, a gene involved in decreasing the likeliness of developing cancer. A mutation in this gene can increase the... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 28-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Lymphoma: This is simply lymphoma involving the small bowel. This can either be lymphoma that is only there or lymphoma that is elsewhere in the body and also i... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 30-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
No: Agranulocytosis is a laboratory finding of no or very low levels of granulocytes, a type of white blood cells. This could be caused by destruction of ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 44-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
It depends: It doesn't usually hurt until the cancer has become large and blocking passage of colon contents or is pushing on something or has spread. Usually it ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 18-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Still possible: In order to diagnose or rule out lymphoma, one needs to look at the involved lymph node under a microscope. Blood tests and x-rays can be helpful howe... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 37-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
It depends: Esophageal cancer can be cured if it is caught early. The prognosis depends largely on the stage of disease. Lower stage disease which is more locali... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 19-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Get checked again: You should go right away to get a check of your complete blood count. Leukemias can arise very quickly and often occur in younger people. Your bruisin... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
It depends: It depends on the type of cancer, characteristics of the cancer, how quickly the cancer is progressing, and other factors. This should be discussed wi... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 20-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Unlikely: Brain tumors are relatively rare and other causes (especially of transient head pain) are much more common. However since this is been going on for tw... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 44-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Not necessarily: An x-ray of the thoracic spine is performed to optimize looking at the bony structure. Furthermore x-rays may not pick up small lesions. A ct scan or ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 62-year-old female asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Risk of spread: Localized prostate cancer is divided in 3 categories, high-risk, intermediate risk and low risk for spreading outside the prostate. This is based on g... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 41-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Change immune state: Immunotherapy can be used to train the immune system to recognize and fight infections or cancer, or to tolerize the immune system to specific allerge... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 34-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Not yet: There are many therapeutic vaccines in clinical trials were brain cancers. Some of these are in advance stage testing. However all of these are still ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 41-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Cancer: Recently several drugs have been approved in the immunotherapy of cancer. These drugs are designed to stimulate the body's immune system to recognize ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 46-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
It depends: Many patients with low risk prostate cancer can undergo active surveillance which doesn't require any treatment and thus no time off work.
Created for people with ongoing healthcare needs but benefits everyone.
A 39-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Redness: The symptoms of paget's disease in the male are similar to that in a female. These include nipple skin redness, mild skin scaling and possibly flaking... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 30-year-old member asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Yes: Endometrial cancer does tend to metastasize in specific patterns. Distant metastases include lung, liver, lymph nodes, brain and vagina. For more in... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 38-year-old male asked:
Dr. James Gulley
Hematology and Oncology 28 years experience
Generally safe: Fine needle aspirations are generally safe. They involve one or more passes of a needle through an area that is to be sampled. I assume that this is i... Read More
Created for people with ongoing healthcare needs but benefits everyone.

Testimonials
Recommendations and Thank you notes are endorsements given from patients or other doctors.

2
Recommendations
243
Thank you notes
HealthTap member
Mar 30, 2015
Dr. Gulley is an amazing doctor! #nationaldoctorsday2015 #virtualflower1
HealthTap member
Mar 31, 2015
Dr. Gulley is an amazing doctor! #nationaldoctorsday2015 #virtualflower1
HealthTap member
This was very helpful. Thanks! My LDH is normal (150) and all labs remain fine. No symptoms at all, very fit. Still, an incidental finding on CT of extensive abdominal and chest lymphandopathy. Biopsy...Read More
HealthTap member
Thanks doc for the idea.. I have a fren who dies just yesterday bcoz of tumor in her ovary, we rily dont know,it just happened so fast.
HealthTap member
Thank you I figured i should probably get it checked, my family has a history of breast cancer so it's been in the back of my mind

Education & Training

Medical/Graduate school

Loma Linda University School of Medicine, CA
Graduated 1995MD

Awards

2010 PECASE (Presidential early career award for scientists and engineers, the highest award bestowed by the US federal government on scientists and engineers early in their careers.)
Thought Leader, Second Place, Washington, DC - Winter
2013
Top Oncologist and Hematologist , Second Place, Maryland - Winter
2013
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