A member asked:

Would getting botox shots every three months affect the liver and kidneys at all?

11 doctors weighed in across 4 answers

No: No are no reports or evidence that long term Botox effects the liver or kidneys.

Answered 6/24/2014

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Dr. Christopher Khorsandi answered

Specializes in Plastic Surgery

No: Botox specifically works at the nerve endings that control muscle function. There is no evidence that it has an effect on either the liver or the kidneys.

Answered 12/27/2014

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Dr. Gurney Pearsall answered

Specializes in Anti-Aging Medicine

No, most likely not: 1) the dose for Botox cosmetic is very small 2) Botox cosmetic works at the injection site as it binds to the target muscle's synaptic junction. It does not float throughout the body affecting organs such as the liver & kidney 3) the cosmetic effect wears off gradually over 3-4 months for face and longer for areas such as the hands.

Answered 1/1/2017

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Dr. Charles Talakkottur answered

Specializes in Internal Medicine

No: It is injected into the muscle and very little systemic absorption(very little goes into the bloodstream).

Answered 5/16/2016

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