A member asked:

Can long-term tramadol use (2 yr, 300mg) cause acalculous gallbladder disease?

A doctor has provided 1 answer
Dr. Daniel Para answered

Specializes in General Surgery

Unlikely: Tramadol does give frequent gastrointestinal side effects such as dyspepsia and nausea, occasional diarrhea, and others. Causing acalculous cholecystitis is not documented. An ultrasound and hida scan will be helpful in diagnosis of the disease.

Answered 12/13/2012

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