What is the best medicine for acid reflux?

Reflux : Many alternatives clearly proto pump inhibitors as a class are superior for controlling sx and contributing to healing.

Zantac (ranitidine) or Pepcid: If you are just starting to be bothered by gerd, then otc zantac (ranitidine) or Pepcid should work well. Those are "h2 blockers" a more potent class of acid-reducing medicine is the ppi class. These include Prilosec and prevacid of course, you should do your part and decrease your intake of peppermint, chocolate, caffeine, alcohol, nicotine, spicy foods, citrus, and carbonated beverages if none work, c ur md.