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A member asked:
What is the definition or description of: scl-70 antibody?
4 doctors weighed in across 2 answers
Autoimmune: Autoantibody to centromere proteins scl-70, topoisomerase 1, found in patients with autoimmune disease and more specific for the autoimmune disease crest (calcinosis, raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia). Can also be found in patients with scleroderma.
Answered 6/10/2016
5.4k views
CREST/ scleroderma: Antibody to a centromere protein, scl-70, found in autoimmune conditions, more specifically crest (calcinosis, raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) and scleroderma.
Answered 11/9/2015
5.4k views
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