Husband on lexapro, (escitalopram) and is mom is paranoid schizophrenia. four of her six siblings had this disease. what are the odds of my kids getting it?

20-22 times more : The odds of your kids getting schizophrenia is approximately 20-25%. Kids grandmother having schizophrenia increases the risk of your kids to have the d/o upto 5% more than general population. Uncles, may add 4%. Your husband's risk of having schizophrenia is approx. 30% b/c of his mother and his 4 siblings.

Significant chances: Schizophrenia is in many cases found to run in familities. Is a complex syndrome with different presentation and symptoms.

Consider this-: Look at it like this. The likelihood of your kids developing schizophrenia are far less then them getting it. And, at the present time, there is nothing we really know which can either cause or prevent it's occurrence. I don't mean to sound at all insensitive and i understand the worry, but it's kind of like the serenity prayer regarding accepting stuff we can't control. Good luck.

Risk: Risk of schizophrenia in general population is 1%. With one afflicted parent is 10%. Two parents 35%. Identical twin is 50%.