A member asked:

Is sickle cell anemia hereditary?

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Yes: Sickle cell anemia is due to a genetic mutation in the dna that encodes for the hemoglobin molecule. Thus, it is hereditary.

Answered 1/26/2018

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Sickle cell disease: Yes. For example, if both parents have sickle cell trait (each have one copy of a sickle beta-hemoglobin gene and one unaffected copy), they have a 25% chance of having a child with sickle cell disease, a 50% chance of the child having sickle cell trait, and a 25% chance of the child having completely normal hemoglobin (no trait or sickle cell disease).

Answered 1/26/2018

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Dr. Richard Roberts answered

Specializes in Pediatrics

Yes.: it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4.

Answered 1/26/2018

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