A member asked:

Is sickle cell anemia inherited trait or sex linked?

2 doctors weighed in across 2 answers

Inherited: Sickle cell anemia is an inherited, non-sex linked genetic mutation ( actually several mutations) that leads to the formation of an abnormal hemoglobin called hemoglobin s. If someone inherits 2 sickle cell genes (1 from each parent), then sickle cell anemia is the result. If only 1 mutation is inherited, sickle cell trait is the result. The gene is passed from parent(s) to children.

Answered 10/7/2013

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not sex-linked: The mutation in hemoglobin that causes sickle cell anemia is not sex-linked.

Answered 12/2/2016

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Could two people with sickle cell trait give their child sickle cell anemia?

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