A member asked:

Can using topamax (topiramate) while you're pregnant cause your child to have a cleft lip?

7 doctors weighed in across 2 answers

Yes: If used in the first trimester, topamax (topiramate) has been linked to cleft lip and palate.

Answered 9/3/2012

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Dr. Joseph Mele answered

Specializes in Plastic Surgery

FDA says yes.: Most cleft lips are associated with a family history and folate (folic acid) deficiency; however, last year the fda notified healthcare professionals and patients of an increased risk of development of cleft lip and/or cleft palate (oral clefts) in infants born to women treated with topamax (topiramate) during pregnancy.

Answered 3/2/2013

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