What causes burning sensation in calves? also pain can run up into the inner thigh not widespread on thigh...clear path of pain. for the past few weeks i've had a burning type pain in both of my calves. the pain sometimes runs up into my inner thigh. the

There : There are several possibilities. 1. Vascular pain-this could be arterial, which is from limited flow of blood because of atherosclerosis of the arteries, or narrowing of the arteries. This pain is usually worse with walking. It could also be venous, like a blood clot, but that pain is usually in one leg. 2. It could be nerve pain, such as a neuropathy of the nerves. 3. You could have an electrolyte imbalance, such as potassium. A low potassium can cause muscle pain. 4. It could be myopathy, or muscle pain. Write down all of your symptoms, what makes the pain worse or better, and see your doctor for an appropriate diagnosis. If you have worsening pain, swelling, fever, redness, or any new symptoms then you must go to the er.