A 42-year-old member asked:
Will cymbalta (duloxetine) stay in my body long enough to taper itself?
2 doctor answers • 8 doctors weighed in
Psychiatry 47 years experience
Variable speed: When one stops taking a drug like cymbalta, (duloxetine) it will leave the body through metabolism and excretion. If it leaves the system too rapidly, a discontinuation syndrome may occur, including vertigo and flu like symptoms. The rate at which the drug leaves the system varies from person to person. So, i always recommend a taper instead of abrupt discontinuation when someone is taking a higher dose.
6.4k viewsReviewed >2 years ago
Psychiatry 42 years experience
No: To get off the medication, it should be tapered
over several days due to its short half life.
It may take about two weeks.
5.6k viewsReviewed Sep 16, 2019
A 40-year-old member asked:
How long will cymbalta (duloxetine) stay in the body?
1 doctor answer • 4 doctors weighed in
Psychiatry 33 years experience
Well......: The half-life of Cymbalta (duloxetine) is about 12 hours. It takes about 5 half-lives for medication to essentially be cleared from your system. However, since some people metabolize the medication more slowly it would be safe to assume the medication would be gone from your system within five days.
5.7k viewsReviewed >2 years ago
Last updated Sep 16, 2019
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