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A 44-year-old member asked:

i have thalassemia minor. my question is, if my husband is normal can my child be born normal too?

3 doctor answers6 doctors weighed in
Dr. Laura Webb
Pediatrics 13 years experience
Yes: Your children will likely be normal, however if your husband is heterozygous for thalassemia (meaning he carries one disease gene and one not) there is a 25% chance your child will be affected and a 50% chance they will be a carrier. Carriers for thalassemia (thalassemia minor) generally are asymptomatic and do not need treatment.
Dr. Anatoly Belilovsky
Pediatrics 35 years experience
Yes: Don't forget, you are normal too - thal minor has very little effect on an individual's health. If your husband is negative for thalassemia trait, the children will either be negative, or at worst with thal-minor, in which case the biggest thing to worry about is having kids with another thal-minor person as the children of two thal-minor parents may be quite seriously ill.
Dr. Robert Kwok
Pediatrics 33 years experience
Yes: If one parent has thalassemia minor, and the other parent has normal hemoglobin (not a carrier of Alpha thal, beta thal, sickle cell, etc...), then the children of the two parents will be normal (have normal hemoglobin), or close to normal (have thal minor). Thal minor generally doesn't cause symptoms. In rare cases, a new or additional mutation could occur and make the situation more complicated.

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Similar questions

India
A 23-year-old female asked:

Im going to marry with my cousin who does not have any thalasemia, while I have b thalassemia minor, will our children have serious problem?

1 doctor answer1 doctor weighed in
Dr. James Ferguson
Pediatrics 46 years experience
Possibly: It is estimated that we all carry at least 4 autosomal recessive genes to conditions that may involve metabolic or other problems like cystic fibrosis.Conditions that hide in the recessive state but can be deadly when two carriers produce an affected child. Cousins are less likely than siblings to have defective kids.In many places it is illegal for sibs and cousins to marry for this reason.

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Last updated May 8, 2018

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