A member asked:

Can you take a decongestant when taking prednisone 20mg ( 2perday for 5days) like mucinex: d ? i was prescribed prednisone for sinus infection

A doctor has provided 1 answer
Dr. Joram Seggev answered

Specializes in Internal Medicine - Allergy & Immunology

Preferably not: Mucinex (guaifenesin) d contains Guaifenesin Pseudoephedrine 120mg which can raise blood pressure, make you jittery, "hyper" and cause heartburn and constipation. Prednisone 40 mg may worsen the side effects, like high blood pressure, thyroid problem or diabetes. You should rinse y our nose with saline and use a nasal decongestant like oxymetazoline (afrin) for 5 days. Guaifenesin may help (mucinex (guaifenesin) without d).

Answered 1/27/2020

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