A member asked:

Is it possible to get the huntington gene even though there's no family history of the disease?

A doctor has provided 1 answer

Yes: Huntington disease is autosomal dominant, meaning that affected individuals have one normal and one abnormal gene. Offspring of an affected parent (like arlo guthrie) have a 50% chance to get the abnormal gene. The expanded trinucleotide repeat that constitutes the abnormal gene can develop as a new mutation without prior cases in the family.

Answered 6/4/2014

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