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A 44-year-old member asked:

Is it possible to get the huntington gene even though there's no family history of the disease?

1 doctor answer2 doctors weighed in
Dr. Golder Wilson
Specializes in Clinical Genetics
Yes: Huntington disease is autosomal dominant, meaning that affected individuals have one normal and one abnormal gene. Offspring of an affected parent (like arlo guthrie) have a 50% chance to get the abnormal gene. The expanded trinucleotide repeat that constitutes the abnormal gene can develop as a new mutation without prior cases in the family.
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Last updated Jun 4, 2014


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