1000-3000 mg/day: There have been only a few studies on this. They do show that l-lysine is highly effective for preventing cold sores. Some studies used doses of 1000 mg 3x/day while others used as little as 1000 mg/day. I usually advise 1500 mg/day. If you still get cold sores try raising the dose- lysine is quite safe.
Answered 12/9/2013
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L-Lysine: Take 1g per day to prevent outbreaks. Increase to 3-9g per day when you have an outbreak.
Answered 9/28/2016
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