Depends on tumor.: The staging of each primary site (breast, lung, etc) is different. In general n0 means no lymph nodes positive. N1 will be limited ln metastases, n2 more extensive, n3 the worst. N1 may be subdivided as n1a, n1b, etc. In general the higher the n number and then the higher the letter in the subset, the worst the prognosis, but anything above n0 means cancer spread to lymph nodes.
Answered 10/3/2016
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