A member asked:

What does having a high 1, 25 oh vitamin d level mean?

A doctor has provided 1 answer
Dr. Michael Rothman answered

Specializes in Internal Medicine

High calcitriol: High Calcitriol (especially if you have normal 25 hydroxy vitamin d) can be a sign of immune system overload. Since 1, 25 dihydroxyvitamin d (calcitriol) down regulates some immune responses, activated macrophages will convert 25 hydroxy into 1, 25 dihydroxy. Many patients with "autoimmune diseases" have this pattern. You must find the cause of your immune system problem.

Answered 6/24/2014

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