Which is the difference between oral lichen planus and oral hairy leukoplakia of the tongue?

Huge difference!: Lichen planus is a submucosal inflammatory lesion usually found on the cheeks. Sometimes ulcers can develop, but this represents little more than an irritating rash. Oral hairy leukoplakia is an opportunistic infection by epstein barr virus. This can be linked to steroid use, hiv, or any other condition causing a reduced immune response.

Only look similar: Although the conditions may take on similar appearance, they're completely different. Oral lichen planus is an autoimmune disorder in which there is inflammation arising from the action of antibodies to the deeper cells of the mucous membrane. Hairy leukoplakia is a thickening of the surface tissues from epstein-barr virus in the presence of a weakened immune system, as might occur in HIV disease.