A member asked:

Is there a difference between chlorhexidine digluconate and chlorhexidine gluconate?

2 doctors weighed in across 2 answers

I believe: Chlorhexidine gluconate (peridex, etc) is the preferred formulation (typically as a 0.12% solution rinse). The digluconate version is typically available in stronger concentrations, and probably have an application, but not used in my practice.

Answered 9/22/2017

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Yes: Chlorhexidine digluconate is a much stronger antimicrobial than the gluconate form.

Answered 8/20/2019

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