A 41-year-old member asked:
What is the difference between chlorhexidine digluconate and chlorhexidine gluconate?
4 doctor answers • 5 doctors weighed in
Dr. Brian Dorfmananswered
Oral and Maxillofacial Surgery 21 years experience
Not much: They work the same way, one product has a slight difference in chemical structure.
Created for people with ongoing healthcare needs but benefits everyone.
5.4k viewsAnswered >2 years ago
Dr. Michael Lebowitzanswered
Dentistry 35 years experience
Chlorhexadine: From researching this question it seems that the active ingredient in the dental rinse is Chlorhexidine gluconate the reference to the digluconate appears in the Periochip form. I do not see the digluconate as the active ingredient in the products we use in dentistry.
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsReviewed >2 years ago
Dr. Behram Dalalanswered
33 years experience
I believe: Chlorhexidine gluconate (peridex, etc) is the preferred formulation (typically as a 0.12% solution rinse). The digluconate version is typically available in stronger concentrations, and probably have an application, but not used in my practice.
Created for people with ongoing healthcare needs but benefits everyone.
5.5k viewsAnswered >2 years agoMerged
Dr. Morey Furmananswered
39 years experience
Yes: Chlorhexidine digluconate is a much stronger antimicrobial than the gluconate form.
Created for people with ongoing healthcare needs but benefits everyone.
5.5k viewsAnswered >2 years agoMerged
Last updated Aug 20, 2019
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