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A 35-year-old member asked:

How does chlorhexidine gluconate work?

3 doctor answers5 doctors weighed in
Dr. Daniel Wolter
Dentistry 31 years experience
Stops Bacteria: Chlorhexidine damages the cell walls of many oral bacteria (and some funguses and viruses), thereby either stopping them from reproducing or killing them directly. Like any medication (including oral rinses), it can have unwanted side effects, so it should only be prescribed by a doctor/dentist and monitored regularly. In low concentrations, it can be quite useful in dentistry for various issues.
Dr. Behram Dalal
32 years experience
Chlorhexadine : Gluconate (peridex (chlorhexidine gluconate) etc) is a very effective topical antiseptic rinse that kills certain bacteria that are responsible for causing gum disease. Important to use as directed. Hope this helps.
Dr. Stanley Siu
Cosmetic Dentistry 18 years experience
Positive attraction: Chlorhexidine gluconate has a positive chemical charge; it is attracted to the negative charge on certain bacteria in the mouth. This attractn affects the bacterial cell membrane & causes increased permeability for immediate antimicrobial activity. Chlorhx is also attracted to neg charged surfs on oral tissue. This additional attractn gives chlorhx sustained action that can help prevent the plaque.

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Last updated Oct 3, 2016
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