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A 70-year-old female asked:

I have been using nose spray for approximately 45 years 2 or more times a day(like afrin (oxymetazoline) and 4-way) could i get cushing' disease and what other side e?

1 doctor answer2 doctors weighed in
Dr. Steven Machtinger
Allergy and Immunology 45 years experience
No: You cannot get cushings' syndrome, the result of taking large amounts of corticosteroids, from decongestant sprays like afrin. You can become and probably are dependent on these sprays, a condition called rhinitis medicamentosa. You also cannot get cushings' from using topical corticosteroid nasal sprays. The dose is just too low to cause such a side-effect.
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Last updated Mar 25, 2014

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