Pcn & Cehalosporins: The conventional number is 10% of penicillin allergic people are also allergic to cephalosporins, however the data is weak since the patient reported incidence of penicillin allergy may only be 10% accurate. There are also 3 generations of cephalosporins and the "cross reactivity" may vary between them. There does seem to be a direct relationship between reaction severity and cross reactivity.
Answered 10/12/2012
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