A member asked:

Since maoi and cigarettes can block mao and raise dopamine levels, can maoi be used to help a smoker quit smoking? if not, why not? if so which maoi?

6 doctors weighed in across 2 answers

No evidence: Dopamine is increased by smoking however although in theory a good question not used options are nicotine replacements varencline nortriptine bupropion etc the risk of side effects is not worth the risk since it is not a first line treatment.

Answered 8/16/2019

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Dr. Heidi Fowler answered

Specializes in Psychiatry

MAOI: MAOI's require strict dietary restrictions and can have very serious side effects. There are many smoking cessation options available. MAOI's should not be used for this purpose.

Answered 8/24/2019

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